The sensitivity and specificity of using the McGill pain subscale for diagnosing neuropathic and non‑neuropathic chronic pain in the total joint arthroplasty population

Authors

  • Dragana Boljanovic‑Susic School of Rehabilitation Sciences, McMaster University, Hamilton, ON, Canada
  • Christina Ziebart Department of Rehabilitation, Western University, 1151 Richmond St. London, ON N6A 3K7 London, Canada
  • Joy MacDermid Department of Rehabilitation, Western University, 1151 Richmond St. London, ON N6A 3K7 London, Canada
  • Justin de Beer Hamilton Arthroplasty Group, Hamilton Health Sciences Juravinski Hospital, Hamilton, ON, Canada
  • Danielle Petruccelli Hamilton Arthroplasty Group, Hamilton Health Sciences Juravinski Hospital, Hamilton, ON, Canada
  • Linda J. Woodhouse McCaig Institute for Bone and Joint Health Calgary, Calgary, AB, Canada

Keywords:

Pain, Arthroplasty, Sensitivity, Specificity

Abstract

Background The purpose of this study was to describe the diagnostic performance of the Neuropathic Pain Subscale of McGill [NP-MPQ (SF-2)] and the Self-Administered Leeds Assessment of Neuropathic Symptoms and Signs (S-LANSS) questionnaire in differentiating people with neuropathic chronic pain post total joint arthroplasty (TJA). Methods This study was a survey of a cohort of individuals who had undergone primary, unilateral total knee, or hip joint arthroplasty. The questionnaires were administered by mail. The time interval from operation to the completion of the postal survey varied from 1.5 to 3.5 years post-surgery. Receiver Operating Characteristic (ROC) analysis was used to assess the overall diagnostic power and determine the optimal threshold value of the NP-MPQ (SF-2) in identification of neuropathic pain. Results S-LANSS identified 19 subjects (28%) as having neuropathic pain (NP), while NP-MPQ (SF-2) subscale identified 29 (43%). When using the S-LANSS as the reference standard, a Receiver Operating Characteristic (ROC) analysis for NP-MPQ (SF-2) had an area under the curve of 0.89 (95% CI: 0.82, 0.97); a cut off score of 0.91 NP-MPQ (SF-2) maximized sensitivity (89.5%) and specificity (75.0%). Correlation between the measures was moderate (r = 0.56; 95% CI: 0.40, 0.68). Conclusion These finding suggest some conceptual overlap but some variability in diagnosis of NP which may relate to scale-tapping into different dimensions of the pain experience, or the different scoring metrics.

References